Extraordinary 2-hour Returns in Exact Sciences Call Options

Bullish option positions are delivering extraordinary profits in Exact Sciences Corporation (EXAS).

Just over two hours ago, today, Nov. 19, Market Rebellion’s Unusual Option Activity Scanners identified significant bullish call buying, with 4,200 21November 72 calls bought in mostly one order for $0.65-$1.04 above the existing open interest of 54 contracts, with EXAS shares trading at $70.60-$71.55.

Those 21November 72 calls traded as high as $16.90 today with the stock at $89.15, delivering extraordinary returns of approximately 1900.00% from the initial midpoint entry price of $0.845. Meanwhile, EXAS shares gained approximately 25.42% from their initial midpoint trading level around $71.08, demonstrating how options can deliver dramatically amplified returns compared to simply owning the underlying stock.

This performance illustrates the exceptional power of options leverage when the directional thesis proves correct, though it’s important to note that this same leverage can work against traders when market moves go in the opposite direction.

Abbott Takeover Reports Trigger Explosive Rally

The primary catalyst driving EXAS’s explosive move came just hours after the unusual call buying activity, with Exact Sciences soaring 28% on November 19, 2025 on a report that Abbott Laboratories is nearing a possible takeover of the medical-testing company, with Abbott discussing the terms of a deal with Exact Sciences. The timing of the call buying at 1:06 PM, followed by the Bloomberg report that triggered the rally, demonstrates the prescient nature of the unusual options activity.

The takeover speculation triggered an immediate and dramatic reaction on Wall Street on November 19, with Exact Sciences shares jumping roughly 25-30% intraday after the first reports suggested Abbott was nearing a possible takeover, with Bloomberg Law reporting Exact Sciences rose as much as 29% and was still up about 19% early in the afternoon, giving the company a market value near $16 billion at one point. For traders positioned in the November 21st expiration calls, this explosive move created ideal conditions for the extraordinary 1900% returns captured in just hours.

EXAS is higher on the session by 20.05% at $83.65.